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Schizophrenia Bulletin 1998 24(1):127-145;
© 1998 by Oxford University Press and the Maryland Psychiatric Research Center (MPRC)
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© Oxford University Press

A Review of Neuropsychological Differences Between Paranoid and Nonparanoid Schizophrenia Patients

Christine Zalewski, Ph.D., Margaret T. Johnson-Selfridge, M.A., Steven Ohriner, M.A., Karen Zarrella, M.A. and James C. Seltzer, Ph.D.
Associate Professor, Pacific Graduate School of Psychology
a Doctoral Student, Pacific Graduate School of Psychology Palo Alto, CA
Private Practice, Redwood City CA
Private Practice, Winter Park FL
Program Director, Schizophrenia Rehabilitation Center, Institute of Living, Hartford Hospital's Mental Health Network Hartford, CT

Reprint requests should be sent to Dr. C. Zalewski, Pacific Graduate School of Psychology, 935 East Meadow Dr., Palo Alto, CA 94303

This review examines the literature on neuropsychological differences between paranoid and nonparanoid schizophrenia subjects. Thirty-two studies related to intellectual functioning, attention, memory, language, visual-spatial, and motor functions are discussed. Subjects with paranoid schizophrenia did not demonstrate higher intellectual functioning than those with nonparanoid schizophrenia, and both groups performed similarly on tests of verbal ability and visual-spatial functions. Several studies suggest that the paranoid subtype is associated with higher performance on tests of executive functions, attention, memory, and motor skills. However, the findings are inconsistent. Methodological issues in the literature are examined, including varying degrees of participants' chronicity and severity of illness among studies, criteria for diagnostic group membership, medication effects, reliability and validity of the neuropsychological measures, and statistical power.

Keywords: Neuropsychology / paranoid / nonparanoid


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