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Schizophrenia Bulletin 2000 26(4):903-912;
© 2000 by Oxford University Press and the Maryland Psychiatric Research Center (MPRC)
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© Oxford University Press

Prevalence and Correlates of Diabetes in National Schizophrenia Samples

Lisa Dixon, M.D., M.P.H., Associate Professor of Pyschiatry, Peter Weiden, M.D., Professor of Psychiatry, Janine Delahanty, M.A., Research Associate, Richard Goldberg, Ph.D., Assistant Professor, Leticia Postrado, Ph.D., Assistant Professor, Alicia Lucksted, Ph.D., Research Associate and Anthony Lehman, M.D., M.S.P.H., Professor
Department of Pyschiatry, University of Maryland Baltimore, MD
State University of New York Health Science Center Brooklyn, New York
Department of Pyschiatry, University of Maryland Baltimore, MD
Department of Pyschiatry, University of Maryland Baltimore, MD
Department of Pyschiatry, University of Maryland Baltimore, MD
Department of Pyschiatry, University of Maryland Baltimore, MD
Department of Pyschiatry, University of Maryland Baltimore, MD

Send reprint requests to Dr. L. Dixon, University of Maryland, Dept. of Psychiatry, 701 West Pratt St., Rm. 476, Baltimore, MD 21201; e-mail: ldixon{at}umaryland.edu

People with schizophrenia may be at increased risk for Type II diabetes because of the side effects of antipsychotic medication, poorer overall physical health, less healthy lifestyles, and poorer health care. The present study uses data bases collected by the Schizophrenia Patient Outcomes Research Team (PORT) to assess the prevalence and demographic and clinical correlates of diabetes within large populations of persons receiving treatment for schizophrenia. In the Schizophrenia PORT, Medicaid and Medicare data from 1991 and more recent interview data were collected regarding the comorbidity of schizophrenia and diabetes: prevalence, quality of life, physical health, and services utilization and costs. The study found that rates of diagnosed diabetes exceeded general population statistics well before the widespread use of the new antipsychotic drugs. Risk factors for diabetes were similar to those observed in the general population. The linkage of diabetes to poor physical health, medical morbidity, and increased service use and cost requires attention. This study of diabetes in the early 1990s suggests that even before the widespread use of the atypical antipsychotic drugs, diabetes was a major problem for persons with schizophrenia.

Keywords: Schizophrenia / diabetes / antipsychotics / hyperglycemia / health services


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