Skip Navigation


Schizophrenia Bulletin Advance Access originally published online on February 9, 2005
Schizophrenia Bulletin 2005 31(1):175-182; doi:10.1093/jschbul/sbi001
This Article
Right arrow Full Text Freely available
Right arrow FREE Full Text (PDF) Freely available
Right arrow All Versions of this Article:
31/1/175    most recent
sbi001v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Bowie, C. R
Right arrow Articles by Harvey, P. D
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Bowie, C. R
Right arrow Articles by Harvey, P. D
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Schizophrenia Bulletin vol. 31 no. 1 © Oxford University Press and the Maryland Psychiatric Research Center 2005; all rights reserved.

Neurocognition, Symptomatology, and Functional Skills in Older Alcohol-Abusing Schizophrenia Patients

Christopher R Bowie, Ph.D.
Instructor, Department of Psychiatry, Mount Sinai School of Medicine, New York, NY

Mark R Serper, Ph.D.
Associate Professor, Department of Psychology, Hofstra University, Hempstead, NY; and Associate Professor, New York University School of Medicine, New York, NY

Silvana Riggio, M.D.
Associate Professor, Department of Psychiatry, Mount Sinai School of Medicine; and Director, Schizophrenia Treatment and Research Program, Mount Sinai School of Medicine/Bronx Veterans Affairs Medical Center

Philip D Harvey, Ph.D.
Professor and Chief of Psychology Services, Department of Psychiatry, Mount Sinai School of Medicine

Send reprint requests to Dr. C.R. Bowie, Mount Sinai School of Medicine, Department of Psychiatry, 1425 Madison Avenue, 4th Floor, New York, NY 10029; e-mail: christopher.bowie{at}mssm.edu.

Deficits in neurocognitive functioning are common to both schizophrenia and alcoholism. Recent studies suggest that neurocognitive functioning is the most significant predictor of social-adaptive functioning in schizophrenia. Cognitive impairment induced by alcoholism may result in more impaired functional outcome for comorbid patients. Past research examining alcohol-abusing schizophrenia patients has not examined correlates with functional outcome and has generally been limited to relatively younger patients. This study examined neurocognitive functioning and its correlates in alcohol-abusing schizophrenia patients between the ages of 40 and 80. Outpatients with schizophrenia (SZ; n = 17) or both schizophrenia and alcohol abuse or dependence (SZ + ETOH; n = 18) were tested on a neurocognitive battery, rated for symptomatology, and assessed for functional abilities. The results suggest that alcohol abuse in schizophrenia is associated with more impaired functioning across many domains, including memory impairment, negative and general psychopathology symptoms, and adaptive functions. The only significant predictor of impaired functional status in the overall sample and the SZ + ETOH group was neurocognitive functioning.

Keywords: Schizophrenia / alcohol / cognition / adaptive functions


Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Am. J. PsychiatryHome page
R. W. Buchanan, D. C. Javitt, S. R. Marder, N. R. Schooler, J. M. Gold, R. P. McMahon, U. Heresco-Levy, and W. T. Carpenter
The Cognitive and Negative Symptoms in Schizophrenia Trial (CONSIST): The Efficacy of Glutamatergic Agents for Negative Symptoms and Cognitive Impairments
Am J Psychiatry, October 1, 2007; 164(10): 1593 - 1602.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.