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Schizophrenia Bulletin Advance Access originally published online on August 3, 2005
Schizophrenia Bulletin 2005 31(4):931-941; doi:10.1093/schbul/sbi038
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© The Author 2005. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oupjournals.org.

Cognitive Remediation and Vocational Rehabilitation for Schizophrenia

Bruce E Wexler
34 Park Street, New Haven, CT 06519
Yale University Department of Psychiatry

Morris D Bell
Yale University Department of Psychiatry
Connecticut Mental Health Center
Veteran Administration's Connecticut Health Center

To whom correspondence should be sent; tel: 203-974-7339, fax: 203-974-7881, e-mail: bruce.wexler{at}yale.edu.

Cognitive deficits are a central and debilitating aspect of schizophrenia and other major mental illnesses. Although they are largely refractory to pharmacotherapy, multiple studies have now shown that large and lasting improvements in cognition can result from behavioral interventions. We will review our work over the past 10 years demonstrating that cognitive remediation treatment together with work therapy or supported employment can lead to large, lasting, and clinically relevant improvements in cognition and work functioning. While we will make some references to the work of others in these same areas, this is not a general review of these areas of research. Instead, the goal is to provide the rationale for the progression of our studies, describe the methods, and summarize the results, so that readers may understand, critique, and improve upon what we have done.

Keywords: schizophrenia / cognitive deficits / cognitive remediation / vocational rehabilitation


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