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Schizophrenia Bulletin Advance Access originally published online on February 21, 2006
Schizophrenia Bulletin 2006 32(2):234-237; doi:10.1093/schbul/sbj055
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© The Author 2006. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

Treatment of Schizophrenia Negative Symptoms: Future Prospects

Stephen M Erhart1,2–3,, Stephen R Marder2, 3, and William T Carpenter4
2 UCLA Department of Psychiatry and Biobehavioral Sciences
3 VISN 22 MIRECC, US Department of Veterans' Affairs
4 University of Maryland School of Medicine, Department of Psychiatry

1To whom correspondence should be addressed; e-mail: serhart{at}ucla.edu.

New findings from neuroscience, genetics, and experimental psychology have emerged that provide alternative explanations of many negative symptoms. We review the continuing limitations in treatment and discuss possible sources of heterogeneity among negative symptoms. We also anticipate conceptual uncertainties that may arise with forthcoming treatment developments.

Keywords: negative symptoms / schizophrenia / treatment / construct validity


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