Schizophrenia Bulletin Advance Access originally published online on September 15, 2005
Schizophrenia Bulletin 2005 31(4):793-794; doi:10.1093/schbul/sbi065
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© The Author 2005. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.
Unmet Therapeutic Needs
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Modern pharmacotherapy for schizophrenia began with the introduction of chlorpromazine in 1952. About the same time principles from social psychiatry were being implemented, and the locus of care shifted away from chronic care hospitals. Empirically validated forms of psychosocial treatment have now joined drug treatment in evidence-based practice. But it has been difficult to robustly alter long-term outcome.1 Current treatments appear most robust in effecting psychosis,2 and there has been
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