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Schizophrenia Bulletin Advance Access originally published online on July 24, 2008
Schizophrenia Bulletin 2008 34(5):813-815; doi:10.1093/schbul/sbn087
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© The Author 2008. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

Haloperidol versus chlorpromazine for treatment of schizophrenia

C. Leucht1,2, M. Kitzmantel3, L. Chua4, J. Kane5 and S. Leucht3
2 Königinstrasse 51, Munich 80539, Germany
3 Klinik für Psychiatrie und Psychotherapie der TU-München, Klinikum rechts der Isar, Ismaningerstrasse 22, 81675 München, Germany
4 Lynfield Mount Hospital, Heights Lane, Bradford BD9 6DP, UK
5 The Zucker Hillside Hospital, Psychiatry Research, Glen Oaks, NY 11004

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   Introduction
 
Chlorpromazine and haloperidol are benchmark antipsychotic drugs which are frequently used as standards in antipsychotic drug trials.1,2 For example, in the review on second-generation antipsychotic drugs by Davis et al.3, haloperidol was by far the most frequently used comparator followed by chlorpromazine. To better define the relative efficacy and safety of both compounds is therefore important for the methodology of randomized . . . [Full Text of this Article]


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   Conflict of interest
 
1 To whom correspondence should be addressed; tel: 089-4140-4249, e-mail: claudialeucht@gmx.de.


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