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Schizophrenia Bulletin 1984 10(3):388-398; doi:10.1093/schbul/10.3.388
© 1984 by Oxford University Press and the Maryland Psychiatric Research Center (MPRC)
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© Oxford University Press

This article appears in the following Schizophrenia Bulletin issue: Featured Topics: Descriptive and Clinical Issues [View the issue table of contents]

The Quality of Life Scale: An Instrument for Rating the Schizophrenic Deficit Syndrome

Douglas W. Heinrichs, M.D., Assistant Professor of Psychiatry, Thomas E. Hanlon, Ph.D., Associate Research Professor and William T. Carpenter, Jr., M.D., Professorof Psychiatry
University of Maryland School of Medicine Baltimore, MD

Reprint requests should be sent to Dr. D.W. Heinrichs, Maryland Psychiatric Research Center, P.O. Box 3235, Baltimore, MD 21228

There is growing interest in deficit symptoms in studies of the course and treatment response of schizophrenia. However, existing clinical assessment instruments focus primarily on productive symptoms. The authors describe the Quality of Life Scale (QLS), a 21-item scale based on a semistructured interview designed to assess deficit symptoms and thereby fill an important gap in the range of instruments now available. Data regarding reliability and training in the use of the QLS are presented. A factor analysis of the items yields results compatible with the conceptual model on which the scale is based. The factor analysis was also performed separately by sex and was fundamentally similar for men and women.


In addition, Dr. Heinrichs is Chief, Outpatient Research Programs, and Dr. Carpenter is Director, Maryland Psychiatric Research Center.


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