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Schizophrenia Bulletin 2004 30(2):193-217;
© 2004 by Oxford University Press and the Maryland Psychiatric Research Center (MPRC)
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© Oxford University Press

The Schizophrenia Patient Outcomes Research Team (PORT): Updated Treatment Recommendations 2003

Anthony F. Lehman, M.D., M.S.P.H., Professor of Psychiatry and Chair, Julie Kreyenbuhl, Pharm.D., Ph.D., Assistant Professor of Psychiatry, Robert W. Buchanan, M.D., Professor of Psychiatry, Faith B. Dickerson, Ph.D., M.P.H., Director of Psychology, Lisa B. Dixon, M.D., M.P.H., Richard Goldberg, Ph.D., Lisa D. Green-Paden, M.D., Wendy N. Tenhula, Ph.D., Daniela Boerescu, M.D., Attending Psychiatrist, Cenk Tek, M.D., Assistant Professor, Neil Sandson, M.D. and Donald M. Steinwachs, Ph.D., Professor and Chair
Department of Psychiatry, University of Maryland School of Medicine, and VA Capital Health Care Network Mental Illness Research, Education and Clinical Center (MIRECC) Baltimore, MD
Department of Psychiatry, University of Maryland School of Medicine, and Investigator, VA Capital Health Care Network MIRECC
Maryland Psychiatric Research Center of the Department of Psychiatry, University of Maryland School of Medicine, and the VA Capital Health Care Network MIRECC
Sheppard Pratt Health System Baltimore, MD
Professor of Psychiatry and Director of Services Research, Department of Psychiatry, University of Maryland School of Medicine; and Associate Director of Research, VA Capital Health Care Network MIRECC
Assistant Professor, Department of Psychiatry, University of Maryland School of Medicine, and Investigator, VA Capital Health Care Network MIRECC
Assistant Professor, Department of Psychiatry, University of Maryland School of Medicine
Assistant Professor, Department of Psychiatry, University of Maryland School of Medicine, and Coordinator, VA Capital Health Care Network MIRECC
Department of Psychiatry, Rhode Island Hospital, Providence
Department of Psychiatry, Dartmouth Medical School Hanover, NH
Clinical Assistant Professor of Psychiatry, University of Maryland School of Medicine and Director, Division of Education and Residency Training, Sheppard Pratt Health System
Department of Health Policy and Management, Bloomberg School of Public Health, Johns Hopkins University Baltimore, MD

Send reprint requests to Dr. A.F. Lehman, Department of Psychiatry, University of Maryland School of Medicine, 701 West Pratt St., Baltimore, MD 21201; e-mail: alehman{at}psych.umaryland.edu

Since publication of the original Schizophrenia Patient Outcomes Research Team (PORT) treatment recommendations in 1998, considerable scientific advances have occurred in our knowledge about how to help persons with schizophrenia. Today an even stronger body of research supports the scientific basis of treatment. This evidence, taken in its entirety, points to the value of treatment approaches combining medications with psychosocial treatments, including psychological interventions, family interventions, supported employment, assertive community treatment, and skills training. The most significant advances lie in the increased options for pharmacotherapy, with the introduction of second generation antipsychotic medications, and greater confidence and specificity in the application of psychosocial interventions. Currently available treatment technologies, when appropriately applied and accessible, should provide most patients with significant relief from psychotic symptoms and improved opportunities to lead more fulfilling lives in the community. Nonetheless, major challenges remain, including the need for (1) better knowledge about the underlying etiologies of the neurocognitive impairments and deficit symptoms that account for much of the disability still associated with schizophrenia; (2) treatments that more directly address functional impairments and that promote recovery; and (3) approaches that facilitate access to scientifically based treatments for patients, the vast majority of whom currently do not have such access.

Keywords: Schizophrenia / mental health services / quality of care / treatment outcomes / pharmacotherapy / psychosocial treatment


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