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Schizophrenia Bulletin Advance Access originally published online on November 20, 2006
Schizophrenia Bulletin 2007 33(1):1-2; doi:10.1093/schbul/sbl062
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© The Author 2006. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

Endophenotypic Studies in Schizophrenia: Promise and Challenges

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The hunt for disease-related genes has proven more difficult than initially appreciated and is successful mostly in disorders that are clearly defined and homogenous. Psychotic disorders have posed a particularly difficult problem due to a lack of preciseness in defining the boundaries of the clinical phenotype and the absence of objective, biological tests that confirm diagnostic categorization. Clinical heterogeneity and the complex nature of schizophrenia and . . . [Full Text of this Article]

Gunvant K. Thaker

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