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Schizophrenia Bulletin Advance Access published online on October 27, 2005
Schizophrenia Bulletin, doi:10.1093/schbul/sbj015
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© The Author 2005. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

Article

Perspectives on Medical Research Involving Men in Schizophrenia and HIV-Related Protocols

Laura Weiss Roberts 1*, Teddy D. Warner 2, Katherine A. Green Hammond 2, and Cynthia M A. Geppert 3
1 Department of Psychiatry and Behavioral Medicine, Medical College of Wisconsin
2 Department of Family and Community Medicine, University of New Mexico School of Medicine
3 New Mexico Veterans Affairs Health Care System and University of New Mexico Health Sciences Center

* To whom correspondence should be addressed.
Laura Weiss Roberts, E-mail: robertsl{at}mcw.edu


  Abstract

Ethical issues in research on serious physical and mental illnesses have received great attention, and yet little is known about how the perspectives of clinical research participants with different diagnoses may compare. We conducted a preliminary study to examine the attitudes of men enrolled in schizophrenia-related protocols and in HIV-related protocols regarding the importance of medical research, key aspects of research participation, and the acceptability of research involvement by various groups. A total of 33 men enrolled in schizophrenia protocols and 15 men enrolled in HIV-related protocols volunteered for our study. Respondents affirmed the importance of medical research and endorsed many positive things about participation. Autonomy and altruism were identified as motivators for research involvement. Participation by diverse groups was seen as acceptable. Respondents expressed comfort and little stress with the interview process. Men in different diagnostic groups largely saw the issues the same. Our findings thus suggest that people with schizophrenia and HIV/AIDS who are enrolled in protocols may share a number of core attitudes or beliefs related to ethical aspects of research participation. Further study is needed to explore how research involvement may influence perspectives and whether differences in views exist across people with diverse physical and mental illnesses.

Keywords: schizophrenia; HIV; research; protocols.
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