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Schizophrenia Bulletin Advance Access published online on January 11, 2006
Schizophrenia Bulletin, doi:10.1093/schbul/sbj037
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© The Author 2006. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. The online version of this article has been published under an open access model. Users are entitled to use, reproduce, disseminate, or display the open access version of this article for non-commercial purposes provided that: the original authorship is properly and fully attributed; the Journal and Oxford University Press are attributed as the original place of publication with the correct citation details given; if an article is subsequently reproduced or disseminated not in its entirety but only in part or as a derivative work this must be clearly indicated. For commercial re-use, please contact journals.permissions@oxfordjournals.org.

Article

The Presence of Neurological Soft Signs Along the Psychosis Proneness Continuum

Emma Barkus 1 *, John Stirling 2, Richard Hopkins 1, and Shôn Lewis 1
1 University of Manchester
2 Manchester Metropolitan University

* To whom correspondence should be addressed.
Emma Barkus, E-mail: emma.j.barkus{at}manchester.ac.uk


  Abstract

Neurological soft signs have been observed in patients with schizophrenia and their relatives. However, it has not been considered whether the increased rates of neurological soft signs are related to measures of psychosis proneness in the general population. We tested this hypothesis in a group of normal volunteers (n = 28) who scored highly for positive schizotypy when assessed online and a control group (n = 33) who scored below the mean. Compared with the controls, high psychosis-prone individuals showed significantly higher Total and Other Soft Signs subscale scores on the Neurological Evaluation Scale. It appears that soft signs are also associated with psychosis proneness when measured in the general population, which suggests that soft signs are distributed along a continuum of risk for schizophrenia.

Keywords: Schizophrenia; neurological soft signs; O-LIFE; hallucinatory proneness.
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