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Schizophrenia Bulletin Advance Access published online on July 18, 2006
Schizophrenia Bulletin, doi:10.1093/schbul/sbl009
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© The Author 2006. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

Co-Occurring Disorders Research

Enhancing Validity in Co-occurring Disorders Treatment Research

Gregory J. McHugo 1 *, Robert E. Drake 1, Mary F. Brunette 1, Haiyi Xie 1, Susan M. Essock 2, and Alan I. Green 3
1 Dartmouth Psychiatric Research Center, 2 Whipple Place, Suite 202, Lebanon, NH 03766
2 Division of Health Services Research, Mt Sinai School of Medicine
3 Department of Psychiatry, Dartmouth Medical School

* To whom correspondence should be addressed.
Gregory J. McHugo, E-mail: gregory.mchugo{at}dartmouth.edu


  Abstract

Despite the high prevalence of co-occurring mental health and substance-use disorders, there has been a relative lack of treatment research with this population, and the existing research often has limited validity. This article explores some of the barriers to the conduct of research on promising interventions for substance-abuse treatment for people with co-occurring disorders, using the concepts of external and ecological validity to make recommendations for future investigation. The central recommendation is to move rapidly from efficacy studies to more credible and valid effectiveness studies, in order to facilitate the adoption of evidence-based interventions in routine practice settings.

Keywords: inferential validity; external validity; ecological validity; co-occurring disorders; dual diagnosis; effectiveness research.
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