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Schizophrenia Bulletin Advance Access published online on June 4, 2007
Schizophrenia Bulletin, doi:10.1093/schbul/sbm065
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© The Author 2007. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

Current Issues in the Classification of Psychotic Major Depression

Jennifer Keller1,2, Alan F. Schatzberg2 and Mario Maj3
2 Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, 401 Quarry Road, Stanford, CA 94305-5723
3 Department of Psychiatry, University of Naples SUN, Naples, Italy

1 To whom correspondence should be addressed; tel: 650-724-0070, fax: 650-723-8331, e-mail: jkeller{at}stanford.edu.

Depression is one of the most common mental disorders worldwide. There are a number of depression subtypes, and there has been much debate about how to most accurately capture and organize the features and subtypes of major depression. We review the current state of categorizing unipolar major depression with psychotic features (psychotic major depression, PMD), including clinical, biological, and treatment aspects of the disorder. We then propose some improvements to the current unipolar major depression categorization system. Finally, we identify important issues in need of further research to help elucidate the subtype of unipolar PMD.

Keywords: major depression / psychosis / classification


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