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Schizophrenia Bulletin Advance Access published online on November 14, 2008

Schizophrenia Bulletin, doi:10.1093/schbul/sbn154
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© The Author 2008. Published by Oxford University Press on behalf of the Maryland Psychiatric Research Center. All rights reserved. For permissions, please email: journals.permissions@oxfordjournals.org.

CNTRICS Final Task Selection: Executive Control

Deanna M. Barch1,2,4 8, Todd S. Braver2, Cameron S. Carter5, Russell A. Poldrack6 and Trevor W. Robbins7
2 Department of Psychology
3 Department of Psychiatry
4 Department of Radiology, Washington University, MO
5 Departments of Psychiatry and Psychology, University of California, Davis, CA
6 Department of Psychology, University of California, Los Angeles, CA
7 Department of Experimental Psychology, University of Cambridge, Cambridge England

1 To whom correspondence should be addressed; Department of Psychology, Washington University, St Louis, MO 63130; tel: 314-935-8729, fax: 314-935-8790, e-mail: dbarch{at}artsci.wustl.edu.

The third meeting of the Cognitive Neuroscience Treatment Research to Improve Cognition in Schizophrenia (CNTRICS) was focused on selecting promising measures for each of the cognitive constructs selected in the first CNTRICS meeting. In the domain of executive control, the 2 constructs of interest were "rule generation and selection" and "dynamic adjustments in control." CNTRICS received 4 task nominations for each of these constructs, and the breakout group for executive control evaluated the degree to which each of these tasks met prespecified criteria. For rule generation and selection, the breakout group for executive control recommended the intradimensional/extradimensional shift task and the switching Stroop for translation for use in clinical trial contexts in schizophrenia research. For dynamic adjustments in control, the breakout group recommended conflict and error adaptation in the Stroop and the stop signal task for translation for use in clinical trials. This article describes the ways in which each of these tasks met the criteria used by the breakout group to recommend tasks for further development.

Keywords: cognition / clinical trials / schizophrenia


8 Co-authors had equivalent input and are listed in alphabetical order.


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